An Efficient, Three-Component Synthesis of 3,4-Di Hydropyrimidin-2(1H)-Ones Using LaCl3/ClCH2COOH as Environmentally Benign and Green Catalytic System
نویسندگان
چکیده مقاله:
An improved, simple, and facile synthesis of 3,4-dihydropyrimidin-2(1H)-ones by employing three-component, one-pot condensation reaction of β-keto ester, aromatic aldehydes, and urea or N-methylurea using LaCl3/ClCH2COOH as an inexpensive and green chemistry catalyst system under solvent-free conditions described. Compared with the classicalBiginelli reaction conditions, this method has the advantages of good to excellent yields (80-99%) and short reaction time.
منابع مشابه
an efficient, three-component synthesis of 3,4-di hydropyrimidin-2(1h)-ones using lacl3/clch2cooh as environmentally benign and green catalytic system
an improved, simple, and facile synthesis of 3,4-dihydropyrimidin-2(1h)-ones by employing three-component, one-pot condensation reaction of β-keto ester, aromatic aldehydes, and urea or n-methylurea using lacl3/clch2cooh as an inexpensive and green chemistry catalyst system under solvent-free conditions described. compared with the classicalbiginelli reaction conditions, this method has the adv...
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عنوان ژورنال
دوره 25 شماره 4
صفحات 323- 327
تاریخ انتشار 2014-12-01
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